Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ABL1 | P00519 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | IDE | P14735 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 5/20 | 0.49 |
| ▸ | CA1 | P00915 | 5/20 | 0.49 |
| ▸ | CA2 | P00918 | 5/20 | 0.49 |
| ▸ | CA9 | Q16790 | 5/20 | 0.49 |
| ▸ | HLCS | P50747 | 6/20 | 0.49 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17371928 | 0.82 | TDP1 (0.59) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL16141162 | 0.81 | TDP1 (0.59) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL2808581 | 0.79 | F2 (0.51) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL22290232 | 0.79 | TDP1 (0.82) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL20887815 | 0.79 | TDP1 (0.67) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL21176811 | 0.78 | TDP1 (0.81) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL28119479 | 0.78 | TDP1 (0.81) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL28283183 | 0.78 | TDP1 (0.81) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL21114407 | 0.78 | TDP1 (0.81) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL24131520 | 0.78 | TDP1 (0.69) | TDP1PKMMEN1ABL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103314114-B | Epigenetic markers for colorectal cancer and diagnostic methods using the same | 临床基因组学股份有限公司 | 2016-08-10 | — | — | CN | disclosed |