Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 19/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 12/20 | 0.60 |
| ▸ | ABCC1 | P33527 | 6/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14320369 | 0.91 | ABCG2 (0.62) | ABCG2ABCB1ABCC1TP53MAPT | |
| SCHEMBL14320419 | 0.90 | ABCG2 (0.68) | ABCG2ABCB1ABCC1TP53MAPT | |
| SCHEMBL14321184 | 0.87 | KDM1A (0.54) | ABCG2ABCB1ABCC1TP53MAPT | |
| SCHEMBL14320776 | 0.85 | RET (0.56) | ABCG2ABCB1ABCC1TP53MAPT | |
| SCHEMBL14320679 | 0.85 | RET (0.56) | ABCG2ABCB1ABCC1 | |
| SCHEMBL14321350 | 0.84 | ABCG2 (0.65) | ABCG2ABCB1ABCC1TP53MAPT | |
| SCHEMBL14321014 | 0.84 | ABCG2 (0.57) | ABCG2ABCB1ABCC1TP53MAPT | |
| SCHEMBL14320291 | 0.84 | SYK (0.51) | ABCG2ABCB1ABCC1TP53MAPT | |
| SCHEMBL14320361 | 0.83 | ABCG2 (0.53) | ABCG2ABCB1ABCC1 | |
| SCHEMBL14320756 | 0.83 | ABCG2 (0.67) | ABCG2ABCB1ABCC1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103492389-B | Pyrazolo [4,3-d] pyrimidine as inhibitors of kinases | 原真股份有限公司 | 2016-09-14 | — | — | CN | disclosed |