Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.70 |
| ▸ | THRB | P10828 | 1/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.70 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.70 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.70 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chlorophacinone SCHEMBL18961 | 0.90 | MEN1 (0.81) | MEN1KMT2AADORA3THRBCHRM1 | |
| Chlorophacinone SCHEMBL29353036 | 0.90 | MEN1 (0.81) | MEN1KMT2AADORA3THRBCHRM1 | |
| Chlorophacinone SCHEMBL11577573 | 0.90 | MEN1 (0.81) | MEN1KMT2AADORA3THRBCHRM1 | |
| Chlorophacinone SCHEMBL29455171 | 0.90 | MEN1 (0.81) | MEN1KMT2AADORA3THRBCHRM1 | |
| Chlorophacinone SCHEMBL4187624 | 0.90 | MEN1 (0.81) | MEN1KMT2AADORA3THRBCHRM1 | |
| Chlorophacinone SCHEMBL9356813 | 0.89 | MEN1 (0.79) | MEN1KMT2AADORA3THRBCHRM1 | |
| Diphenadione SCHEMBL43891 | 0.84 | MEN1 (1.00) | MEN1KMT2AADORA3THRBCHRM1 | |
| Diphenadione SCHEMBL19815987 | 0.84 | MEN1 (1.00) | MEN1KMT2AADORA3THRBCHRM1 | |
| Diphenadione SCHEMBL29405205 | 0.84 | MEN1 (1.00) | MEN1KMT2AADORA3THRBCHRM1 | |
| Diphenadione SCHEMBL1651307 | 0.82 | MEN1 (0.96) | MEN1KMT2AADORA3THRBCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103492389-B | Pyrazolo [4,3-d] pyrimidine as inhibitors of kinases | 原真股份有限公司 | 2016-09-14 | — | — | CN | disclosed |