Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 20/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13739328 | 0.90 | NAMPT (0.64) | NAMPTCYP2C9 | |
| SCHEMBL13740149 | 0.90 | NAMPT (0.64) | NAMPTCYP2C9 | |
| SCHEMBL13739269 | 0.90 | NAMPT (0.64) | NAMPTCYP2C9 | |
| SCHEMBL13740492 | 0.90 | NAMPT (0.65) | NAMPTCYP2C9 | |
| SCHEMBL13738474 | 0.89 | NAMPT (0.62) | NAMPTCYP2C9 | |
| SCHEMBL13739624 | 0.88 | NAMPT (0.62) | NAMPTCYP2C9 | |
| SCHEMBL13739613 | 0.88 | NAMPT (0.62) | NAMPTCYP2C9 | |
| SCHEMBL29944175 | 0.88 | NAMPT (0.63) | NAMPTCYP2C9 | |
| SCHEMBL13741063 | 0.88 | NAMPT (0.63) | NAMPTCYP2C9 | |
| SCHEMBL13740809 | 0.87 | NAMPT (0.60) | NAMPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103874686-B | Piperidine derivatives and compositions for inhibition of nicotinamide phosphoribosyltransferase (NAMPT) | 福马TM有限责任公司 | 2016-08-17 | — | — | CN | claimed |