SCHEMBL28088263

SCHEMBL28088263

CCc1c[c]ccc1.F[B-](F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.41
IDO1 P14902 1/20 0.32
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL58507 0.91
SCHEMBL28195226 0.89
SCHEMBL27593502 0.87 TP53 (0.44) TP53IDO1CYP2A6
SCHEMBL27765919 0.83 TP53 (0.41) TP53CYP2A6
SCHEMBL28140800 0.79 TP53 (0.37) TP53
SCHEMBL27430888 0.78 TP53 (0.44) TP53CYP2A6
SCHEMBL2256246 0.75 BCL2 (0.47) TP53IDO1CYP2A6
SCHEMBL128292 0.74
SCHEMBL1370559 0.73 TP53 (0.39) TP53CYP2A6
SCHEMBL230025 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104540871-B The preparation method of aromatic compound 住友化学株式会社 2016-08-24 CN disclosed