Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.75 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.73 |
| ▸ | USP2 | O75604 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.69 |
| ▸ | OSBP | P22059 | 1/20 | 0.69 |
| ▸ | RORC | P51449 | 1/20 | 0.69 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.69 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.61 |
| ▸ | GBA1 | P04062 | 2/20 | 0.60 |
| ▸ | UGCG | Q16739 | 2/20 | 0.60 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.60 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11497304 | 1.00 | POLA1 (0.75) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL8839992 | 1.00 | POLA1 (0.75) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL8608988 | 1.00 | POLA1 (0.75) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL28273010 | 1.00 | POLA1 (0.75) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL28404863 | 0.99 | POLA1 (0.73) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL8425524 | 0.99 | POLA1 (0.73) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL29356325 | 0.99 | POLA1 (0.73) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL8961810 | 0.99 | POLA1 (0.73) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL27101999 | 0.99 | POLA1 (0.73) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL3954236 | 0.99 | POLA1 (0.76) | POLA1CYP46A1USP2LMNAABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105859815-B | The synthetic method of 7- ketone group cholesterine -9- carboxyl nonane and its fluorescent marker | 大连大学 | 2019-07-16 | — | — | CN | claimed |
| CN-105859815-A | 7-keto cholesteryl-9-carboxyl nonane and synthesis method of fluorescent marker thereof | 大连大学 | 2016-08-17 | — | — | CN | claimed |
| CN-105859815-B | The synthetic method of 7- ketone group cholesterine -9- carboxyl nonane and its fluorescent marker | 大连大学 | 2019-07-16 | — | — | CN | disclosed |
| CN-105859815-A | 7-keto cholesteryl-9-carboxyl nonane and synthesis method of fluorescent marker thereof | 大连大学 | 2016-08-17 | — | — | CN | disclosed |