SCHEMBL28089103

SCHEMBL28089103

Cn1cc(-c2c(O)c(-c3cc(S(C)(=O)=O)ccc3OCC3CC3)cn(C)c2=O)cn1

nearest known ligand 0.61

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 20/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28341611 0.92 BRD4 (0.57) BRD4
SCHEMBL29849033 0.83 BRD4 (0.81) BRD4
SCHEMBL16651547 0.83 BRD4 (0.81) BRD4
SCHEMBL16658189 0.83 BRD4 (0.65) BRD4
SCHEMBL16651137 0.81 BRD4 (0.69) BRD4
SCHEMBL29848683 0.81 BRD4 (0.69) BRD4
SCHEMBL16658175 0.80 BRD4 (0.78) BRD4
SCHEMBL21931497 0.78 BRD4 (0.62) BRD4
SCHEMBL16651342 0.78 BRD4 (0.68) BRD4
SCHEMBL20155050 0.78 BRD4 (0.72) BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108558889-B Bromodomain inhibitors 赛尔基因昆蒂赛尔研究公司 2021-11-05 CN claimed
CN-105828820-A Bromodomain inhibitors 赛尔基因昆蒂赛尔研究公司 2016-08-03 CN claimed
CN-108558889-B Bromodomain inhibitors 赛尔基因昆蒂赛尔研究公司 2021-11-05 CN disclosed
CN-105828820-B Bromodomain inhibitors 赛尔基因昆蒂赛尔研究公司 2020-01-07 CN disclosed
CN-105828820-A Bromodomain inhibitors 赛尔基因昆蒂赛尔研究公司 2016-08-03 CN disclosed