Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Sulfide SCHEMBL28135070 | 0.88 | TSHR (0.67) | TSHRALDH1A1TDP1THRBCES2 | |
| Isobutane SCHEMBL27408068 | 0.88 | TSHR (0.75) | TSHRALDH1A1TDP1THRBOPRM1 | |
| SCHEMBL28162033 | 0.88 | TSHR (0.75) | TSHRALDH1A1TDP1THRBOPRM1 | |
| Isobutane SCHEMBL27724406 | 0.85 | TSHR (0.71) | TSHRALDH1A1TDP1THRBOPRM1 | |
| SCHEMBL28113334 | 0.85 | TSHR (0.71) | TSHRALDH1A1TDP1THRBOPRM1 | |
| SCHEMBL27890170 | 0.84 | — | — | |
| SCHEMBL3164 | 0.84 | — | — | |
| Hexane SCHEMBL8845002 | 0.84 | TSHR (0.92) | TSHRALDH1A1TDP1THRBFAAH | |
| SCHEMBL276808 | 0.84 | — | — | |
| SCHEMBL9285670 | 0.84 | TSHR (0.92) | TSHRALDH1A1TDP1THRBFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106054523-B | A kind of degradable photoresist of double-response type and preparation method thereof and application method | 北京化工大学 | 2019-10-18 | — | — | CN | claimed |
| CN-106054523-A | Double response type degradable photoresist as well as preparation method and use method therefor | 北京化工大学 | 2016-10-26 | — | — | CN | claimed |
| CN-106054523-B | A kind of degradable photoresist of double-response type and preparation method thereof and application method | 北京化工大学 | 2019-10-18 | — | — | CN | disclosed |
| CN-109641908-A | Five-ring heterocycles simultaneously [3,4-d] pyridazinone compound, preparation method, pharmaceutical composition and its application | 中国科学院上海药物研究所 | 2019-04-16 | — | — | CN | disclosed |
| CN-109562107-A | Heterocyclic degrading ligand for target protein degradation | C4医药公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-105777756-B | Heteroaryl compound and its application in drug | 广东东阳光药业有限公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-109305967-A | New pyrimidine and heterocycle compound and preparation method and purposes | 中国科学院上海药物研究所 | 2019-02-05 | — | — | CN | disclosed |
| CN-107383004-A | 2 aminooimidazoles and pyridine derivatives and preparation and application | 浙江大学 | 2017-11-24 | — | — | CN | disclosed |
| CN-106243044-A | Pyridine derivatives containing halo acrylamide side chain and preparation and application | 浙江大学 | 2016-12-21 | — | — | CN | disclosed |
| CN-106054523-A | Double response type degradable photoresist as well as preparation method and use method therefor | 北京化工大学 | 2016-10-26 | — | — | CN | disclosed |
| CN-105777756-A | Heteroaryl compound and application thereof in medicines | 广东东阳光药业有限公司 | 2016-07-20 | — | — | CN | disclosed |