Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28815746 | 0.79 | BACE1 (0.33) | MEN1GAAKMT2ABACE1 | |
| SCHEMBL27992357 | 0.73 | BACE1 (0.32) | BACE1 | |
| SCHEMBL28089970 | 0.72 | MEN1 (0.35) | MEN1GAAKMT2A | |
| SCHEMBL27992353 | 0.72 | MEN1 (0.30) | MEN1GAAKMT2A | |
| SCHEMBL28815743 | 0.72 | MEN1 (0.38) | MEN1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL27992358 | 0.72 | BACE1 (0.31) | MEN1GAAKMT2ABACE1 | |
| Ethane SCHEMBL27992354 | 0.71 | BACE1 (0.30) | MEN1GAAKMT2ABACE1 | |
| SCHEMBL27926107 | 0.67 | BACE1 (0.37) | MEN1GAAKMT2ABACE1SMN1; SMN2 | |
| SCHEMBL27992341 | 0.66 | BACE1 (0.36) | MEN1GAAKMT2ABACE1CSNK2A2 | |
| SCHEMBL27925977 | 0.66 | BACE1 (0.36) | MEN1GAAKMT2ABACE1CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104277004-B | Prepare method and its intermediate of pyridazinone compound | 住友化学株式会社 | 2016-08-24 | — | — | CN | disclosed |