Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CCR1 | P32246 | 3/20 | 0.35 |
| ▸ | CCR5 | P51681 | 3/20 | 0.35 |
| ▸ | CCR8 | P51685 | 3/20 | 0.35 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.32 |
| ▸ | S100A4 | P26447 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27503 | 0.96 | — | — | |
| Water SCHEMBL14695895 | 0.92 | TDP1 (0.45) | TDP1HDAC8HSP90AA1LMNASMN1; SMN2 | |
| Fluoride SCHEMBL27617026 | 0.92 | — | — | |
| Ammonia Solution, Strong SCHEMBL1644542 | 0.92 | — | — | |
| SCHEMBL28569786 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL11399498 | 0.92 | — | — | |
| Hydrazine SCHEMBL22129483 | 0.89 | — | — | |
| SCHEMBL9167898 | 0.89 | — | — | |
| Formaldehyde SCHEMBL27625151 | 0.86 | TDP1 (0.41) | TDP1HDAC8HSP90AA1LMNASMN1; SMN2 | |
| Methylamine SCHEMBL27900642 | 0.86 | HSP90AA1 (0.42) | TDP1HDAC8HSP90AA1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104003944-B | A kind of preparation method of mepanipyrim | 西北师范大学 | 2016-08-24 | — | — | CN | disclosed |