Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.58 |
| ▸ | IDO1 | P14902 | 3/20 | 0.50 |
| ▸ | PNMT | P11086 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL320795 | 0.98 | TAAR1 (0.60) | TAAR1IDO1PNMTSLC6A2SLC6A4 | |
| SCHEMBL29447950 | 0.98 | TAAR1 (0.60) | TAAR1IDO1PNMTSLC6A2SLC6A4 | |
| SCHEMBL6681501 | 0.84 | TAAR1 (0.56) | TAAR1IDO1PNMTSLC6A2SLC6A4 | |
| SCHEMBL6679599 | 0.82 | TAAR1 (0.54) | TAAR1IDO1PNMTSLC6A2SLC6A4 | |
| SCHEMBL6740216 | 0.82 | TAAR1 (0.71) | TAAR1IDO1PNMTSLC6A2SLC6A4 | |
| SCHEMBL8071207 | 0.80 | TAAR1 (0.52) | TAAR1IDO1PNMTSLC6A2SLC6A4 | |
| SCHEMBL7563447 | 0.80 | TAAR1 (0.52) | TAAR1IDO1PNMTSLC6A2SLC6A4 | |
| SCHEMBL7562209 | 0.80 | TAAR1 (0.52) | TAAR1IDO1PNMTSLC6A2SLC6A4 | |
| SCHEMBL8070948 | 0.80 | TAAR1 (0.52) | TAAR1IDO1PNMTSLC6A2SLC6A4 | |
| SCHEMBL7562064 | 0.80 | TAAR1 (0.52) | TAAR1IDO1PNMTSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105939996-A | Dihydropyridone and dihydropyridazinone derivatives as bromodomain inhibitors | 艾伯维公司 | 2016-09-14 | — | — | CN | disclosed |