SCHEMBL28093046

SCHEMBL28093046

C=CC(=O)Cl.CCCCCCl

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.52
ALDH1A1 P00352 4/20 0.52
ZDHHC20 Q5W0Z9 2/20 0.44
ZDHHC2 Q9UIJ5 2/20 0.44
TDP1 Q9NUW8 1/20 0.43
HPGD P15428 1/20 0.42
FAAH O00519 4/20 0.41
TP53 P04637 1/20 0.41
THRB P10828 5/20 0.38
THRA P10827 4/20 0.38
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexane SCHEMBL29250870 0.91 TSHR (0.50) TSHRALDH1A1ZDHHC20ZDHHC2HPGD
Acrylic Acid SCHEMBL28403837 0.86 TSHR (0.52) TSHRALDH1A1ZDHHC20ZDHHC2TDP1
Acrylic Acid SCHEMBL27618977 0.84 TSHR (0.56) TSHRALDH1A1ZDHHC20ZDHHC2TDP1
Acrylic Acid SCHEMBL27961272 0.84 TSHR (0.50) TSHRALDH1A1ZDHHC20ZDHHC2TDP1
Acrylic Acid SCHEMBL5480845 0.84 TSHR (0.56) TSHRALDH1A1ZDHHC20ZDHHC2TDP1
Acrylamide SCHEMBL28822294 0.84 TSHR (0.50) TSHRALDH1A1ZDHHC20ZDHHC2TDP1
SCHEMBL27759501 0.83 TSHR (0.67) TSHRALDH1A1TDP1FAAHTP53
Dodecanol SCHEMBL28349554 0.80 TSHR (0.56) TSHRALDH1A1ZDHHC20ZDHHC2HPGD
SCHEMBL28536289 0.78 TSHR (0.60) TSHRALDH1A1TDP1FAAHTP53
SCHEMBL10773744 0.78 TSHR (0.68) TSHRALDH1A1TDP1FAAHCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107142110-A A kind of preparation method of chemical sand-fixing materialses 闫博文 2017-09-08 CN claimed
CN-107142110-A A kind of preparation method of chemical sand-fixing materialses 闫博文 2017-09-08 CN disclosed
CN-103755672-B A kind of specificity fluorescent probe for identifying cysteine and application thereof 大连理工常熟研究院有限公司 2016-08-17 CN disclosed