Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20341737 | 0.83 | KMT2A (0.49) | KMT2APOLBMEN1CYP3A4CYP2C19 | |
| SCHEMBL11900963 | 0.81 | KMT2A (0.50) | KMT2AMEN1CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL1442422 | 0.79 | KMT2A (0.46) | KMT2APOLBMEN1CYP3A4CYP2C19 | |
| SCHEMBL28798054 | 0.78 | KMT2A (0.51) | KMT2AMEN1CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL692548 | 0.78 | KMT2A (0.48) | KMT2AMEN1CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL268273 | 0.78 | KMT2A (0.48) | KMT2AMEN1CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL268274 | 0.78 | KMT2A (0.48) | KMT2AMEN1CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL3804273 | 0.77 | KMT2A (0.47) | KMT2APOLBMEN1CYP3A4CYP2C19 | |
| Hydrochloric Acid SCHEMBL30831586 | 0.77 | KMT2A (0.47) | KMT2AMEN1CYP3A4CYP2C19ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5561971 | 0.77 | KMT2A (0.47) | KMT2AMEN1CYP3A4CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105980387-B | Serine/threonine kinase inhibitor | 阵列生物制药公司 | 2019-04-19 | — | — | CN | disclosed |
| CN-105980387-A | Serine/threonine kinase inhibitors | 阵列生物制药公司 | 2016-09-28 | — | — | CN | disclosed |