Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 14/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | SHBG | P04278 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14046282 | 1.00 | CYP19A1 (0.76) | CYP19A1CYP3A4LMNAMAPTSHBG | |
| SCHEMBL11020843 | 0.86 | CYP19A1 (1.00) | CYP19A1CYP3A4LMNAMAPTSHBG | |
| SCHEMBL13001778 | 0.86 | CYP19A1 (1.00) | CYP19A1CYP3A4LMNAMAPTSHBG | |
| SCHEMBL4361013 | 0.86 | CYP19A1 (1.00) | CYP19A1CYP3A4LMNAMAPTSHBG | |
| SCHEMBL12430769 | 0.86 | CYP19A1 (1.00) | CYP19A1CYP3A4LMNAMAPTSHBG | |
| SCHEMBL15903 | 0.86 | CYP19A1 (1.00) | CYP19A1CYP3A4LMNAMAPTSHBG | |
| SCHEMBL13787743 | 0.86 | CYP19A1 (1.00) | CYP19A1CYP3A4LMNAMAPTSHBG | |
| SCHEMBL13994334 | 0.86 | CYP19A1 (0.74) | CYP19A1CYP3A4LMNAMAPT | |
| SCHEMBL4431797 | 0.86 | CYP19A1 (1.00) | CYP19A1CYP3A4LMNAMAPTSHBG | |
| SCHEMBL13752636 | 0.86 | CYP19A1 (1.00) | CYP19A1CYP3A4LMNAMAPTSHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428796-A | S (alkynyl of 4 (the methylbutyryl epoxide of 3 fluorine 3) fourth 2) 6 α, the crystal form of the β carbothioic acid esters of 1,4 diene of the α of 9 α difluoros 17 (base of furans 2) carbonyloxy group 11 β hydroxyls, 16 α methyl, 3 oxoandrost 17 | 太阳医药高级研究有限公司 | 2017-12-01 | — | — | CN | claimed |
| CN-106520693-B | Memory B cell precursor and application thereof | 清华大学 | 2019-11-22 | — | — | CN | disclosed |
| CN-110003192-A | Substituted amino-metadiazine compound and its application method and purposes | 广东东阳光药业有限公司 | 2019-07-12 | — | — | CN | disclosed |
| CN-106478651-B | Substituted heteroaryl compound and combinations thereof and purposes | 广东东阳光药业有限公司 | 2019-07-09 | — | — | CN | disclosed |
| CN-105367555-B | Substituted heteroaryl compound and combinations thereof and purposes | 广东东阳光药业有限公司 | 2019-06-25 | — | — | CN | disclosed |
| CN-105130966-B | Alkynyl compounds and its application method and purposes | 广东东阳光药业有限公司 | 2019-05-24 | — | — | CN | disclosed |
| CN-106478607-B | Substituted heteroaryl compound and combinations thereof and purposes | 广东东阳光药业有限公司 | 2019-05-24 | — | — | CN | disclosed |
| CN-105461694-B | Substituted heteroaryl compound and combinations thereof and purposes | 广东东阳光药业有限公司 | 2019-05-24 | — | — | CN | disclosed |
| CN-109776522-A | Substituted heteroaryl compound and combinations thereof and purposes | 广东东阳光药业有限公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-109438543-A | A kind of preparation method of high-purity fluticasone furoate | 广州健康元呼吸药物工程技术有限公司 | 2019-03-08 | — | — | CN | disclosed |
| CN-104926794-B | Substituted heteroaryl compound and combinations thereof and purposes | 广东东阳光药业有限公司 | 2017-12-05 | — | — | CN | disclosed |
| CN-107428796-A | S (alkynyl of 4 (the methylbutyryl epoxide of 3 fluorine 3) fourth 2) 6 α, the crystal form of the β carbothioic acid esters of 1,4 diene of the α of 9 α difluoros 17 (base of furans 2) carbonyloxy group 11 β hydroxyls, 16 α methyl, 3 oxoandrost 17 | 太阳医药高级研究有限公司 | 2017-12-01 | — | — | CN | disclosed |
| CN-104926795-B | Substituted heteroaryl compound and combinations thereof and purposes | 广东东阳光药业有限公司 | 2017-11-10 | — | — | CN | disclosed |
| CN-104650092-B | Substituted heteroaryl compound and combinations thereof and purposes | 广东东阳光药业有限公司 | 2017-11-10 | — | — | CN | disclosed |
| CN-104672250-B | Substituted heteroaryl compound and combinations thereof and purposes | 广东东阳光药业有限公司 | 2017-11-07 | — | — | CN | disclosed |
| CN-104974163-B | Substituted heteroaryl compound and combinations thereof and purposes | 广东东阳光药业有限公司 | 2017-11-07 | — | — | CN | disclosed |
| CN-107106516-A | Pharmaceutical combination product | 葛兰素史克知识产权开发有限公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-107072976-A | Pharmaceutical composition comprising Danirixin for the treatment of infectious diseases | 葛兰素史克知识产权第二有限公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-104926824-B | Substituted heteroaryl compound and combinations thereof and purposes | 广东东阳光药业有限公司 | 2017-07-07 | — | — | CN | disclosed |
| CN-106029140-A | Inhaler | 鲁平有限公司 | 2016-10-12 | — | — | CN | disclosed |