Pyridine

Pyridine

SCHEMBL28095262

Clc1ccc[nH]1.c1ccncc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.41
TSHR P16473 1/20 0.41
NAPRT Q6XQN6 1/20 0.41
SLC6A2 P23975 2/20 0.33
SLC6A4 P31645 2/20 0.33
SLC6A3 Q01959 2/20 0.33
NOTUM Q6P988 1/20 0.32
CYP19A1 P11511 2/20 0.31
CYP2A6 P11509 1/20 0.31
CFTR P13569 1/20 0.30
GOPC Q9HD26 1/20 0.30
MTOR P42345 1/20 0.30
ADK P55263 1/20 0.30
NISCH Q9Y2I1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL28852031 0.89 MAPT (0.34) TDP1TSHRNAPRT
SCHEMBL673620 0.83
SCHEMBL27760249 0.80
SCHEMBL7119113 0.80
Pyridine SCHEMBL28105792 0.73 TDP1 (0.47) TDP1TSHRNAPRTSLC6A2SLC6A4
Pyridine SCHEMBL27908760 0.73 TSHR (0.41) TDP1TSHRNAPRTSLC6A2SLC6A4
Pyridine SCHEMBL15263781 0.73 TSHR (0.41) TDP1TSHRNAPRTSLC6A2SLC6A4
Pyridine SCHEMBL27629170 0.73 TSHR (0.41) TDP1TSHRNAPRTSLC6A2SLC6A4
Pyridine SCHEMBL28270231 0.73 TSHR (0.41) TDP1TSHRNAPRTSLC6A2SLC6A4
Pyridine SCHEMBL28104080 0.73 NAPRT (0.41) TDP1TSHRNAPRTSLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106316932-A Method for preparing 2,3-dichloro-5-trichloromethylpyridine from DCTF distillation and rapid-steaming residues 盐城工学院 2017-01-11 CN disclosed
CN-105923828-A Method for treating pyridine wastewater 浙江奇彩环境科技股份有限公司 2016-09-07 CN disclosed