Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 5/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 5/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 5/20 | 0.41 |
| ▸ | GCLC | P48506 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 5/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.37 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.37 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.37 |
| ▸ | CASR | P41180 | 2/20 | 0.36 |
| ▸ | GRM8 | O00222 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1768513 | 1.00 | PMP22 (0.42) | PMP22SLC1A3SLC1A2SLC1A1GCLC | |
| SCHEMBL1768945 | 0.82 | SLC7A5 (0.45) | PMP22SLC1A3SLC1A2SLC1A1GCLC | |
| SCHEMBL27872394 | 0.82 | SLC7A5 (0.45) | PMP22SLC1A3SLC1A2SLC1A1GCLC | |
| SCHEMBL8441116 | 0.81 | PMP22 (0.48) | PMP22SLC1A3SLC1A2SLC1A1GCLC | |
| SCHEMBL31688971 | 0.81 | PMP22 (0.48) | PMP22SLC1A3SLC1A2SLC1A1GCLC | |
| SCHEMBL8441119 | 0.81 | PMP22 (0.48) | PMP22SLC1A3SLC1A2SLC1A1GCLC | |
| SCHEMBL13584739 | 0.80 | PMP22 (0.48) | PMP22SLC1A3SLC1A2SLC1A1GCLC | |
| SCHEMBL27888845 | 0.80 | PMP22 (0.48) | PMP22SLC1A3SLC1A2SLC1A1GCLC | |
| SCHEMBL1768843 | 0.78 | PTGS1 (0.41) | PMP22SLC1A3SLC1A2SLC1A1GCLC | |
| SCHEMBL28961753 | 0.78 | PTGS1 (0.41) | PMP22SLC1A3SLC1A2SLC1A1SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102844327-B | Template-fixed peptidomimetics with CXCR7 modulatory activity | 波利弗尔股份公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-102712676-B | There is the peptidomimetic that the template of CCR10 antagonistic activity is fixing | 波利弗尔股份公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-102844327-A | Template-fixed peptidomimetics with CXCR7 modulatory activity | POLYPHOR AG | 2012-12-26 | — | — | CN | disclosed |
| CN-102712676-A | Template-fixed peptidomimetics with CCR10 antagonistic activty | POLYPHOR AG | 2012-10-03 | — | — | CN | disclosed |