Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 8/20 | 0.61 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.61 |
| ▸ | GRM3 | Q14832 | 4/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | GRM8 | O00222 | 2/20 | 0.61 |
| ▸ | GRM6 | O15303 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | GRM5 | P41594 | 1/20 | 0.61 |
| ▸ | MTOR | P42345 | 1/20 | 0.61 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.61 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952657 | 1.00 | GRM4 (0.61) | GRM4GRM2GRM3CYP1A2CYP2C19 | |
| SCHEMBL29952939 | 1.00 | GRM4 (0.61) | GRM4GRM2GRM3CYP1A2CYP2C19 | |
| SCHEMBL5663760 | 0.87 | GRM4 (0.52) | GRM4GRM2GRM3CYP1A2CYP2C19 | |
| SCHEMBL5663765 | 0.87 | GRM4 (0.52) | GRM4GRM2GRM3CYP1A2CYP2C19 | |
| SCHEMBL544530 | 0.86 | GRM4 (0.54) | GRM4GRM2GRM3CYP1A2CYP2C19 | |
| SCHEMBL160783 | 0.86 | GRM4 (0.54) | GRM4GRM2GRM3CYP1A2CYP2C19 | |
| SCHEMBL912861 | 0.86 | GRM4 (0.54) | GRM4GRM2GRM3CYP1A2CYP2C19 | |
| SCHEMBL15060220 | 0.80 | — | — | |
| SCHEMBL25492415 | 0.76 | GRM4 (0.59) | GRM4GRM2GRM3CYP1A2CYP2C19 | |
| SCHEMBL2157698 | 0.76 | GRM4 (1.00) | GRM4GRM2GRM3CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102414177-B | Compounds as bradykinin B1 antagonists | BOEHRINGER INGELHEIM INT | 2014-07-02 | — | — | CN | disclosed |
| US-20130131075-A1 | NEW COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-05-23 | — | — | US | disclosed |
| CN-101336232-B | 3' -alkoxy-spirocyclopentyl-substituted tetramic and tetronic acids | BAYER CROPSCIENCE AG | 2012-08-29 | — | — | CN | disclosed |
| CN-102414177-A | Compounds as bradykinin b1 antagonists | BOEHRINGER INGELHEIM INT | 2012-04-11 | — | — | CN | disclosed |
| US-20100240669-A1 | NEW COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-23 | — | — | US | disclosed |
| CN-101336232-A | 3' -alkoxy-spirocyclopentyl-substituted tetramic and tetronic acids | BAYER CROPSCIENCE AG (DE) | 2008-12-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131075-A1 | NEW COMPOUNDS | ADORA1, H1-10, P2RY11 | GRM4 1150/4885GRM2 1098/4885GRM3 459/4885 |
| US-20100240669-A1 | NEW COMPOUNDS | ADORA1, H1-10, P2RY11 | GRM4 1150/4885GRM2 1098/4885GRM3 459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.