Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28095654 | 1.00 | AKR1C3 (0.52) | AKR1C3SMPD1HDAC1HDAC8HDAC6 | |
| SCHEMBL28276811 | 0.91 | AKR1C3 (0.63) | AKR1C3SMPD1HDAC1HDAC8HDAC6 | |
| SCHEMBL7429368 | 0.85 | TNFRSF1A (0.58) | AKR1C3SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL12507687 | 0.81 | ABCG2 (0.59) | AKR1C3SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL30159756 | 0.81 | ABCG2 (0.59) | AKR1C3SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL28673604 | 0.81 | PDE4A (0.53) | AKR1C3MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL27948969 | 0.81 | PDE4A (0.53) | AKR1C3MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9047043 | 0.75 | SRD5A2 (0.65) | SMPD1HDAC1HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL28278126 | 0.75 | SMN1; SMN2 (0.53) | SMPD1HDAC1HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL7814134 | 0.74 | AKR1C3 (0.71) | AKR1C3SMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105924380-A | Phenanthrene Compound, Ramification Thereof And Drug Composition Containing Phenanthrene Compound Or Ramification And Used For Treating Tuberculosis | 顺天乡大学校产学协力团 | 2016-09-07 | — | — | CN | disclosed |