Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28069227 | 0.77 | — | — | |
| SCHEMBL27675540 | 0.75 | — | — | |
| SCHEMBL27354844 | 0.70 | — | — | |
| Bromide SCHEMBL28272603 | 0.70 | — | — | |
| SCHEMBL27758685 | 0.67 | — | — | |
| SCHEMBL5303684 | 0.65 | — | — | |
| SCHEMBL28199192 | 0.63 | — | — | |
| SCHEMBL5329952 | 0.62 | FYN (0.30) | — | |
| SCHEMBL9019836 | 0.56 | — | — | |
| SCHEMBL24717329 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105949129-B | A kind of imidazoles bromide ionic liquid and its preparation method and application with amino | 辽宁大学 | 2019-02-19 | — | — | CN | claimed |
| CN-105949129-B | A kind of imidazoles bromide ionic liquid and its preparation method and application with amino | 辽宁大学 | 2019-02-19 | — | — | CN | disclosed |
| CN-106045913-B | A kind of imidazoles perrhenate ions liquid and its preparation method and application with amino | 辽宁大学 | 2018-10-26 | — | — | CN | disclosed |
| CN-106045913-A | Imidazolium perrhenate ionic liquid with amino groups as well as preparation method and application of imidazolium perrhenate ionic liquid | 辽宁大学 | 2016-10-26 | — | — | CN | disclosed |
| CN-105949129-A | Imidazolium bromide ionic liquid containing amine groups and preparation method and application of ionic liquid | 辽宁大学 | 2016-09-21 | — | — | CN | disclosed |