SCHEMBL28096084

SCHEMBL28096084

CCCCCCCCCC[Si](C)(C)CCl

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.46
ALDH1A1 P00352 3/20 0.46
THRB P10828 1/20 0.42
TDP1 Q9NUW8 1/20 0.36
PLA2G1B P04054 1/20 0.34
HSP90AA1 P07900 1/20 0.34
RAD52 P43351 1/20 0.34
ATG4B Q9Y4P1 1/20 0.34
DNM1 Q05193 5/20 0.33
LMNA P02545 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
FAAH O00519 1/20 0.33
HSD17B10 Q99714 1/20 0.33
SLC22A1 O15245 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL992167 1.00 TSHR (0.46) TSHRALDH1A1THRBTDP1PLA2G1B
SCHEMBL20856792 1.00 TSHR (0.46) TSHRALDH1A1THRBTDP1PLA2G1B
SCHEMBL993499 1.00 TSHR (0.46) TSHRALDH1A1THRBTDP1PLA2G1B
SCHEMBL1644059 0.97 TSHR (0.41) TSHRALDH1A1THRBTDP1PLA2G1B
SCHEMBL1644055 0.89
SCHEMBL10356295 0.83 TSHR (0.53) TSHRALDH1A1THRBDNM1LMNA
SCHEMBL8388564 0.83 TSHR (0.53) TSHRALDH1A1THRBDNM1LMNA
SCHEMBL10356297 0.83 TSHR (0.53) TSHRALDH1A1THRBDNM1LMNA
SCHEMBL10356347 0.83 TSHR (0.53) TSHRALDH1A1THRBDNM1LMNA
SCHEMBL19119178 0.83 TSHR (0.53) TSHRALDH1A1THRBDNM1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105925971-B Environment-friendly type film agent 中山市东升镇威尔特表面技术厂 2018-02-27 CN disclosed
CN-105925971-A Environmental-friendly coating agent 中山市东升镇威尔特表面技术厂 2016-09-07 CN disclosed