Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL27318173 | 0.85 | HTR2C (0.44) | HTR3AHTR2CSLC18A3SIGMAR1TDP1 | |
| Tert-Butyl Formate SCHEMBL27950764 | 0.85 | HTR2C (0.44) | HTR3AHTR2CSLC18A3SIGMAR1TDP1 | |
| Tert-Butyl Formate SCHEMBL27674643 | 0.85 | HTR2C (0.44) | HTR2CSLC18A3SIGMAR1TDP1 | |
| Tert-Butyl Formate SCHEMBL27562128 | 0.85 | HTR2C (0.47) | HTR2CSLC18A3SIGMAR1HTR6TDP1 | |
| Tert-Butyl Formate SCHEMBL28014693 | 0.85 | HTR2C (0.44) | HTR3AHTR2CSLC18A3SIGMAR1TDP1 | |
| Tert-Butyl Formate SCHEMBL27488567 | 0.85 | SLC18A3 (0.62) | HTR2CSLC18A3SIGMAR1HTR6TDP1 | |
| Tert-Butyl Formate SCHEMBL28123133 | 0.84 | HTR2C (0.43) | HTR2CSLC18A3SIGMAR1TDP1 | |
| Tert-Butyl Formate SCHEMBL28096208 | 0.83 | HTR2C (0.42) | HTR2CSLC18A3SIGMAR1TDP1 | |
| Tert-Butyl Formate SCHEMBL27745536 | 0.82 | HTR2C (0.44) | HTR2CSLC18A3SIGMAR1TDP1 | |
| Tert-Butyl Formate SCHEMBL28096562 | 0.82 | HTR2C (0.41) | HTR2CSLC18A3SIGMAR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061963-B | Heterocyclic modulators of lipid synthesis and combinations thereof | 3-V生物科学股份有限公司 | 2019-10-22 | — | — | CN | disclosed |
| CN-106061963-A | Heterocyclic modulators of lipid synthesis and combinations thereof | 3-V生物科学股份有限公司 | 2016-10-26 | — | — | CN | disclosed |