Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 15/20 | 0.84 |
| ▸ | LCK | P06239 | 9/20 | 0.67 |
| ▸ | JAK3 | P52333 | 5/20 | 0.67 |
| ▸ | EGFR | P00533 | 3/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16764410 | 0.91 | BTK (1.00) | BTKLCKJAK3EGFR | |
| SCHEMBL16764120 | 0.91 | BTK (1.00) | BTKLCKJAK3EGFR | |
| SCHEMBL16763559 | 0.88 | BTK (1.00) | BTKLCKJAK3EGFR | |
| SCHEMBL16763558 | 0.88 | BTK (1.00) | BTKLCKJAK3EGFR | |
| SCHEMBL16763731 | 0.88 | BTK (1.00) | BTKLCKJAK3EGFR | |
| SCHEMBL16763729 | 0.88 | BTK (1.00) | BTKLCKJAK3EGFR | |
| SCHEMBL16763676 | 0.87 | BTK (1.00) | BTKLCKJAK3EGFR | |
| SCHEMBL16763674 | 0.87 | BTK (1.00) | BTKLCKJAK3EGFR | |
| SCHEMBL16763854 | 0.86 | BTK (0.91) | BTKLCKJAK3EGFR | |
| SCHEMBL16763852 | 0.86 | BTK (0.91) | BTKLCKJAK3EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105960404-A | Inhibitors of bruton's tyrosine kinase | 药品循环有限责任公司 | 2016-09-21 | — | — | CN | disclosed |