SCHEMBL28096378

SCHEMBL28096378

O=C(O)c1ccc(C(=O)O)c(-c2cccc(C(=O)O)c2-c2cc(C(=O)O)ccc2C(=O)O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
LMNA P02545 1/20 0.50
MAPT P10636 1/20 0.50
PTPN1 P18031 1/20 0.49
TTR P02766 2/20 0.47
PTPRC P08575 2/20 0.46
MYC P01106 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
KDM4E B2RXH2 1/20 0.46
POLB P06746 2/20 0.45
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
NPC1 O15118 1/20 0.44
GAA P10253 1/20 0.44
RAB9A P51151 1/20 0.44
GFER P55789 1/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA6 P23280 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10782535 0.91 PTPN1 (0.53) ALDH1A1LMNAMAPTPTPN1TTR
SCHEMBL5668163 0.88 PTPRC (0.56) ALDH1A1LMNAMAPTPTPN1TTR
SCHEMBL5667748 0.88 PTPRC (0.56) ALDH1A1LMNAMAPTPTPN1TTR
SCHEMBL10787725 0.85 TTR (0.58) ALDH1A1PTPN1TTRPTPRCMYC
SCHEMBL10782282 0.84 PTPN1 (0.50) PTPN1TTRPTPRCMYCKDM4E
SCHEMBL29370227 0.83 KDM4E (0.55) MAPTPTPN1TTRPTPRCMYC
SCHEMBL29699465 0.83 KDM4E (0.55) MAPTPTPN1TTRPTPRCMYC
SCHEMBL7633476 0.83 KDM4E (0.55) MAPTPTPN1TTRPTPRCMYC
SCHEMBL10492712 0.80 POLB (0.70) ALDH1A1LMNAMAPTTTRPTPRC
SCHEMBL10526597 0.80 TTR (0.67) ALDH1A1LMNAMAPTPTPN1TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106046032-B A kind of metal-organic framework material, synthetic method and its catalytic applications that is constructed based on 5-membered aromatic carboxylic acid 三峡大学 2017-03-15 CN disclosed
CN-106076419-B A kind of load type metal organic frame composite, preparation method and applications 三峡大学 2017-03-15 CN disclosed
CN-106046032-A MOF (metal-organic framework) material constructed on basis of pentabasic aromatic carboxylic acid as well as synthesis method and catalytic application of MOF material 三峡大学 2016-10-26 CN disclosed