Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 15/20 | 0.58 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9968864 | 0.89 | S1PR1 (0.69) | S1PR1S1PR3NPC1ALDH1A1 | |
| SCHEMBL2808433 | 0.87 | S1PR1 (0.62) | S1PR1S1PR3NPC1ALDH1A1NR1H4 | |
| SCHEMBL2809462 | 0.80 | S1PR1 (0.75) | S1PR1S1PR3NPC1ALDH1A1 | |
| SCHEMBL406485 | 0.79 | S1PR1 (0.66) | S1PR1S1PR3NPC1ALDH1A1NR1H4 | |
| SCHEMBL410638 | 0.79 | S1PR1 (0.64) | S1PR1S1PR3NPC1ALDH1A1NR1H4 | |
| SCHEMBL2806695 | 0.79 | S1PR1 (0.72) | S1PR1S1PR3NPC1ALDH1A1 | |
| SCHEMBL2806926 | 0.79 | S1PR1 (0.74) | S1PR1S1PR3NPC1 | |
| SCHEMBL13127443 | 0.79 | S1PR1 (0.71) | S1PR1S1PR3NPC1ALDH1A1 | |
| SCHEMBL2806786 | 0.79 | S1PR1 (0.71) | S1PR1S1PR3NPC1ALDH1A1 | |
| SCHEMBL2791385 | 0.78 | S1PR1 (0.67) | S1PR1S1PR3NPC1ALDH1A1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8202865-B2 | Oxadiazole derivatives | MERCK SERONO SA (CH) | 2012-06-19 | — | — | US | disclosed |
| US-20100240658-A1 | Oxadiazole Derivatives | MERCK SERONO SA (CH) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240658-A1 | Oxadiazole Derivatives | OXA1L, RO60, NQO2 | S1PR1 483/4885S1PR3 335/4885NPC1 4814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.