Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ASPH | Q12797 | 1/20 | 0.40 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7114177 | 0.84 | HSD17B10 (0.44) | CYP1A2TDP1MAPTALDH1A1GPR35 | |
| SCHEMBL7833774 | 0.79 | HSD17B10 (0.48) | CYP1A2TDP1ALDH1A1GPR35MEN1 | |
| SCHEMBL169340 | 0.79 | MAPT (0.44) | CYP1A2TDP1MAPTALDH1A1GPR35 | |
| SCHEMBL601391 | 0.79 | ATM (0.46) | CYP1A2TDP1MAPTALDH1A1GPR35 | |
| SCHEMBL4737907 | 0.79 | MAPT (0.44) | CYP1A2TDP1MAPTALDH1A1GPR35 | |
| SCHEMBL4725428 | 0.79 | MAPT (0.44) | CYP1A2TDP1MAPTALDH1A1GPR35 | |
| SCHEMBL4737915 | 0.79 | MAPT (0.44) | CYP1A2TDP1MAPTALDH1A1GPR35 | |
| SCHEMBL27661939 | 0.79 | MAPT (0.44) | CYP1A2TDP1MAPTALDH1A1GPR35 | |
| SCHEMBL601392 | 0.79 | ATM (0.46) | CYP1A2TDP1MAPTALDH1A1GPR35 | |
| Hydrochloric Acid SCHEMBL11248291 | 0.77 | ATM (0.45) | CYP1A2TDP1MAPTALDH1A1GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110354128-A | Pyrimidine FGFR4 inhibitors | 卫材R&D管理有限公司 | 2019-10-22 | — | — | CN | disclosed |
| CN-105899490-B | Pyrimidine FGFR4 Inhibitors | 卫材R&D管理有限公司 | 2019-07-23 | — | — | CN | disclosed |
| CN-105899490-A | Pyrimidine fgfr4 inhibitors | 卫材R&D管理有限公司 | 2016-08-24 | — | — | CN | disclosed |