Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.58 |
| ▸ | PTGDR2 | Q9Y5Y4 | 13/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28096994 | 0.90 | TMEM97 (0.67) | TMEM97SIGMAR1PTGDR2NPC1RAB9A | |
| SCHEMBL29554819 | 0.85 | TMEM97 (0.58) | TMEM97SIGMAR1PTGDR2NPC1RAB9A | |
| SCHEMBL4795463 | 0.85 | TMEM97 (0.58) | TMEM97SIGMAR1PTGDR2NPC1RAB9A | |
| SCHEMBL30276669 | 0.85 | TMEM97 (0.58) | TMEM97SIGMAR1PTGDR2NPC1RAB9A | |
| SCHEMBL28097001 | 0.85 | PTGDR2 (0.60) | TMEM97SIGMAR1PTGDR2 | |
| SCHEMBL324228 | 0.83 | TMEM97 (0.67) | TMEM97SIGMAR1NPC1RAB9AMEN1 | |
| SCHEMBL24495279 | 0.82 | TMEM97 (0.58) | TMEM97SIGMAR1PTGDR2NPC1RAB9A | |
| SCHEMBL15056801 | 0.81 | PTGDR2 (0.59) | TMEM97SIGMAR1PTGDR2MEN1ALDH1A1 | |
| SCHEMBL15056744 | 0.81 | PTGDR2 (0.62) | TMEM97SIGMAR1PTGDR2MEN1ALDH1A1 | |
| SCHEMBL16269012 | 0.81 | TMEM97 (0.53) | TMEM97SIGMAR1PTGDR2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104011021-B | heterocyclic derivatives and their use as prostaglandin D2 receptor modulators | 埃科特莱茵药品有限公司 | 2016-08-24 | — | — | CN | disclosed |