Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Ethyl Cinnamate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA7 | P43166 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Cinnamate SCHEMBL28267661 | 0.89 | CA12 (0.68) | CA12CA7CA9CA14CA1 | |
| Ethyl Cinnamate SCHEMBL1866942 | 0.89 | CA12 (0.72) | CA12CA7CA9CA14CA1 | |
| Ethyl Cinnamate SCHEMBL112445 | 0.89 | CA12 (0.72) | CA12CA7CA9CA14CA1 | |
| Ethyl Cinnamate SCHEMBL112446 | 0.89 | CA12 (0.72) | CA12CA7CA9CA14CA1 | |
| Ethyl Cinnamate SCHEMBL12001792 | 0.89 | CA12 (0.72) | CA12CA7CA9CA14CA1 | |
| Ethyl Cinnamate SCHEMBL28542490 | 0.88 | CA12 (0.70) | CA12CA7CA9CA14CA1 | |
| Ethyl Cinnamate SCHEMBL28278949 | 0.88 | CA12 (0.70) | CA12CA7CA9CA14CA1 | |
| Ethyl Cinnamate SCHEMBL27295428 | 0.88 | CA12 (0.70) | CA12CA7CA9CA14CA1 | |
| Ethyl Cinnamate SCHEMBL27872803 | 0.88 | CA12 (0.70) | CA12CA7CA9CA14CA1 | |
| Ethyl Cinnamate SCHEMBL27295429 | 0.88 | CA12 (0.70) | CA12CA7CA9CA14CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106281685-A | A kind of Cortex Cinnamomi odor type cigar flavouring essence for tobacco and its preparation method and application | 湖北中烟工业有限责任公司 | 2017-01-04 | — | — | CN | disclosed |