SCHEMBL28097710

SCHEMBL28097710

CC(=O)C1=C(O)C(CC2=C(O)C(C)(C)C(=O)C(C(C)=O)=C2O)=C(O)C(C)(C)C1=O

nearest known ligand 0.82

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ FASN P49327 8/20 0.82
▸ ALDH1A1 P00352 1/20 0.32
▸ POLB P06746 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ AKR1B10 O60218 1/20 0.31
▸ ALOX5 P09917 1/20 0.31
▸ KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30212090 0.91 FASN (1.00) FASNKDM4EMEN1AKR1B10ALOX5
SCHEMBL30212070 0.88 FASN (0.82) FASNKDM4EMEN1AKR1B10ALOX5
SCHEMBL30212099 0.80 FASN (0.91) FASNALDH1A1KDM4EMEN1AKR1B10
SCHEMBL29466102 0.78 FASN (0.91) FASNALOX5
SCHEMBL28043703 0.77 FASN (0.89) FASNALOX5
SCHEMBL30212096 0.76 FASN (1.00) FASN
SCHEMBL30212074 0.75 FASN (0.56) FASNALOX5
SCHEMBL30212075 0.75 FASN (0.53) FASNALDH1A1KDM4EMEN1ALOX5
SCHEMBL30212041 0.75 FASN (0.80) FASNALOX5
SCHEMBL30212065 0.74 FASN (0.72) FASNALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12178790-B2 Antibacterial compound isolated from Psiloxylon mauritianum and its derivatives SORRES, Jonathan (FR) 2024-12-31 — — US disclosed
CN-116270567-A Pharmaceutical preparation for treating diabetes 山东中医药大学附属医院 2023-06-23 — — CN disclosed
US-20230062900-A1 NEW ANTIBACTERIAL COMPOUND ISOLATED FROM PSILOXYLON MAURITIANUM AND ITS DERIVATIVES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2023-03-02 — — US disclosed
CN-106038900-A Medicine composition for treating diabetic nephropathy and preparation method thereof 济南星懿医药技术有限公司 2016-10-26 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230062900-A1 NEW ANTIBACTERIAL COMPOUND ISOLATED FROM PSILOXYLON MAURITIANUM AND ITS DERIVATIVES PNN, AAAS, MRPS35 FASN 37/4885ALDH1A1 2230/4885POLB 1460/4885
US-12178790-B2 Antibacterial compound isolated from Psiloxylon mauritianum and its derivatives AAAS, PNN, MRPL9 FASN 27/4885ALDH1A1 2151/4885POLB 1796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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