SCHEMBL2809780

SCHEMBL2809780

C=Cc1ccsc1-c1cccs1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
KDM4E B2RXH2 5/20 0.36
MAPT P10636 3/20 0.36
HPGD P15428 3/20 0.36
ALDH1A1 P00352 3/20 0.36
TDP1 Q9NUW8 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
DPP4 P27487 1/20 0.34
ERN1 O75460 2/20 0.34
CYP3A4 P08684 2/20 0.33
CYP2C9 P11712 2/20 0.33
LTA4H P09960 2/20 0.33
CYP2E1 P05181 1/20 0.33
CYP2A6 P11509 1/20 0.33
CYP2B6 P20813 1/20 0.33
HSD17B10 Q99714 3/20 0.33
TSHR P16473 1/20 0.33
POLB P06746 1/20 0.32
NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14603424 0.98 DPP4 (0.37) MEN1KMT2AKDM4EMAPTHPGD
SCHEMBL15259644 0.89 MEN1 (0.33) MEN1KMT2AKDM4EMAPTHPGD
SCHEMBL2524602 0.88 PTPRC (0.33) MEN1KMT2AKDM4EMAPTHPGD
Dipyridyl SCHEMBL15872117 0.83 SMN1; SMN2 (0.44) MEN1KMT2AKDM4EMAPTHPGD
SCHEMBL9231804 0.80 ERN1 (0.49) MEN1KMT2AKDM4EMAPTHPGD
SCHEMBL9950992 0.80 MEN1 (0.37) MEN1KMT2AKDM4EMAPTHPGD
SCHEMBL5804666 0.79 DPP4 (0.30) DPP4
SCHEMBL975367 0.76 DPP4 (0.39) MEN1KMT2AKDM4EMAPTHPGD
SCHEMBL28623649 0.76 MEN1 (0.34) MEN1KMT2AKDM4EMAPTHPGD
SCHEMBL15259643 0.76 MEN1 (0.34) MEN1KMT2AKDM4EMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9063434-B2 Sub-diffraction-limited patterning and imaging via multi-step photoswitching UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2015-06-23 US claimed
US-20140199636-A1 SUB-DIFFRACTION-LIMITED PATTERNING AND IMAGING VIA MULTI-STEP PHOTOSWITCHING UNIVERSITY OF UTAH 2014-07-17 US claimed
CN-118930821-A Conjugated polymer containing ethylene glycol side chain bithiazole unit and preparation method and application thereof 中国科学院长春应用化学研究所 2024-11-12 CN disclosed
US-10642074-B2 Photonic modulator structures and methods of manufacture UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2020-05-05 US disclosed
US-20180095300-A1 PHOTONIC MODULATOR STRUCTURES AND METHODS OF MANUFACTURE UNIVERSITY OF UTAH 2018-04-05 US disclosed
US-9703211-B2 Sub-diffraction-limited patterning and imaging UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2017-07-11 US disclosed
US-20160109811-A1 SUB-DIFFRACTION-LIMITED PATTERNING AND IMAGING UNIVERSITY OF UTAH 2016-04-21 US disclosed
US-9164369-B2 Patterning via optical-saturable transitions MASSACHUSETTES INSTITUTE OF TECHNOLOGY (US) 2015-10-20 US disclosed
US-9063434-B2 Sub-diffraction-limited patterning and imaging via multi-step photoswitching UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2015-06-23 US disclosed
US-20140199636-A1 SUB-DIFFRACTION-LIMITED PATTERNING AND IMAGING VIA MULTI-STEP PHOTOSWITCHING UNIVERSITY OF UTAH 2014-07-17 US disclosed
WO-2010117776-A2 PATTERNING VIA OPTICAL-SATURABLE TRANSITIONS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2010-10-14 WO disclosed
US-20100248159-A1 PATTERNING VIA OPTICAL-SATURABLE TRANSISIONS MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2010-09-30 US disclosed
US-20100221646-A1 HOLOGRAPHIC RECORDING MEDIUM KABUSHIKI KAISHA TOSHIBA (JP) 2010-09-02 US disclosed