Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 3/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.47 |
| ▸ | CDC7 | O00311 | 1/20 | 0.47 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 3/20 | 0.46 |
| ▸ | MAP3K14 | Q99558 | 3/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | CDK4 | P11802 | 1/20 | 0.45 |
| ▸ | PRKACA | P17612 | 3/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30507501 | 0.81 | CDK2 (0.52) | CDK2CCNE1CDC7DBF4MAP3K14 | |
| SCHEMBL28497712 | 0.81 | CDK2 (0.52) | CDK2CCNE1CDC7DBF4MAP3K14 | |
| SCHEMBL13425430 | 0.80 | MAP3K14 (0.59) | CDK2CCNE1CDC7JAK2MAP3K14 | |
| SCHEMBL3103196 | 0.79 | PRKACA (0.56) | CDK2CCNE1CDC7JAK2MAP3K14 | |
| SCHEMBL27497962 | 0.77 | JAK2 (0.47) | CDK2CCNE1CDC7JAK2MAP3K14 | |
| SCHEMBL24732287 | 0.76 | CCR1 (0.64) | MAPTKDM4EALDH1A1NPSR1TLR8 | |
| SCHEMBL3395606 | 0.75 | ADORA2A (0.44) | HSP90AA1ADORA2AMAPTKDM4EALDH1A1 | |
| SCHEMBL13977469 | 0.74 | JAK2 (0.76) | CDK2CDC7JAK2CCNA2CDK9 | |
| SCHEMBL29488164 | 0.74 | GSK3B (0.71) | CDK2MAP3K14CCNT1CCNA2CDK9 | |
| SCHEMBL23175317 | 0.74 | GSK3B (0.71) | CDK2MAP3K14CCNT1CCNA2CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106046197-A | Compound having bacteriostatic activity and preparation and application thereof | 中国科学院海洋研究所 | 2016-10-26 | — | — | CN | disclosed |