SCHEMBL28098347

SCHEMBL28098347

CC12CC3CC(C1)CC(C)(C3)C2.NNC(=O)NN

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
EPHX2 P34913 5/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
GRIN1 Q05586 3/20 0.38
GRIN2A Q12879 3/20 0.38
LMNA P02545 2/20 0.38
GRIN2D O15399 2/20 0.38
GRIN3B O60391 2/20 0.38
GRIN2B Q13224 2/20 0.38
GRIN2C Q14957 2/20 0.38
GRIN3A Q8TCU5 2/20 0.38
SLC22A1 O15245 1/20 0.38
ESR1 P03372 1/20 0.38
ADRB3 P13945 1/20 0.38
ACHE P22303 1/20 0.38
OPRK1 P41145 1/20 0.38
MTOR P42345 1/20 0.38
HTT P42858 1/20 0.38
EPHX1 P07099 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28098358 0.84 TSHR (0.49) TSHREPHX2MEN1KMT2ALMNA
SCHEMBL28098360 0.82 GRIN1 (0.41) TSHREPHX2MEN1KMT2AGRIN1
Acetamide SCHEMBL2553577 0.81 TSHR (0.50) TSHREPHX2MEN1KMT2AGRIN1
Methyl Alcohol SCHEMBL28225130 0.78 TSHR (0.48) TSHREPHX2MEN1KMT2AGRIN1
Acetamide SCHEMBL28027672 0.78 TSHR (0.47) TSHREPHX2MEN1KMT2AGRIN1
SCHEMBL3190483 0.78 GRIN1 (0.48) TSHREPHX2MEN1KMT2AGRIN1
SCHEMBL733849 0.78 GRIN1 (0.48) TSHREPHX2MEN1KMT2AGRIN1
SCHEMBL3821518 0.76 TSHR (0.54) TSHREPHX2GRIN1GRIN2AGRIN2D
Dimethylamine SCHEMBL4774387 0.75 GRIN1 (0.50) TSHREPHX2MEN1KMT2AGRIN1
Hydrochloric Acid SCHEMBL28669825 0.75 GRIN1 (0.50) TSHREPHX2MEN1KMT2AGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104592035-B A kind of synthetic method of 1,3-diaminourea-5,7-dimethyladamantane 中钢集团鞍山热能研究院有限公司 2016-08-24 CN claimed
CN-104592035-B A kind of synthetic method of 1,3-diaminourea-5,7-dimethyladamantane 中钢集团鞍山热能研究院有限公司 2016-08-24 CN disclosed
CN-104592035-B A kind of synthetic method of 1,3-diaminourea-5,7-dimethyladamantane 中钢集团鞍山热能研究院有限公司 2016-08-24 CN disclosed