Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.61 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.61 |
| ▸ | AURKA | O14965 | 1/20 | 0.61 |
| ▸ | CDK1 | P06493 | 1/20 | 0.61 |
| ▸ | NEK2 | P51955 | 1/20 | 0.61 |
| ▸ | PLK1 | P53350 | 1/20 | 0.61 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.43 |
| ▸ | EED | O75530 | 3/20 | 0.35 |
| ▸ | SUZ12 | Q15022 | 3/20 | 0.35 |
| ▸ | EZH2 | Q15910 | 3/20 | 0.35 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.35 |
| ▸ | RBBP7 | Q16576 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 8/20 | 0.34 |
| ▸ | TDO2 | P48775 | 8/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Viridin SCHEMBL150042 | 0.94 | APP (0.68) | APPPIK3CAAURKACDK1NEK2 | |
| Viridin SCHEMBL150041 | 0.94 | APP (0.68) | APPPIK3CAAURKACDK1NEK2 | |
| Viridin SCHEMBL12162187 | 0.94 | APP (0.68) | APPPIK3CAAURKACDK1NEK2 | |
| Viridin SCHEMBL11235085 | 0.83 | APP (0.55) | APPPIK3CAAURKACDK1NEK2 | |
| SCHEMBL19194687 | 0.81 | APP (0.72) | APPPIK3CAAURKACDK1NEK2 | |
| Demethoxyviridin SCHEMBL12464244 | 0.76 | APP (1.00) | APPPIK3CAAURKACDK1NEK2 | |
| Demethoxyviridin SCHEMBL12162246 | 0.76 | APP (1.00) | APPPIK3CAAURKACDK1NEK2 | |
| Demethoxyviridin SCHEMBL29745916 | 0.76 | APP (1.00) | APPPIK3CAAURKACDK1NEK2 | |
| SCHEMBL8226303 | 0.76 | APP (0.68) | APPPIK3CAAURKACDK1NEK2 | |
| SCHEMBL18270602 | 0.76 | APP (0.68) | APPPIK3CAAURKACDK1NEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107921113-A | Immunomodulatory compositions and methods of use thereof | 巴比塔·阿格拉沃尔 | 2018-04-17 | — | — | CN | disclosed |
| CN-106102771-A | Immunomodulatory compositions and methods of use thereof | 巴比塔·阿格拉沃尔 | 2016-11-09 | — | — | CN | disclosed |