Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL28098407

CCOc1ccc(OCC)c(NC(=O)c2ccccc2)c1.N

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.80
HDAC1 Q13547 3/20 0.70
HDAC8 Q9BY41 3/20 0.70
HDAC6 Q9UBN7 3/20 0.70
MAPT P10636 5/20 0.64
TSHR P16473 3/20 0.64
MAPK1 P28482 1/20 0.64
CREBBP Q92793 2/20 0.62
GAA P10253 2/20 0.62
PLAU P00749 1/20 0.61
ALDH1A1 P00352 2/20 0.60
KDM4E B2RXH2 2/20 0.60
NPC1 O15118 3/20 0.59
MEN1 O00255 2/20 0.59
RAB9A P51151 2/20 0.59
KMT2A Q03164 2/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
POLB P06746 1/20 0.58
HTT P42858 1/20 0.58
LMNA P02545 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30434017 0.99 EPHX1 (0.77) EPHX1HDAC1HDAC8HDAC6MAPT
SCHEMBL1756430 0.99 EPHX1 (0.77) EPHX1HDAC1HDAC8HDAC6MAPT
Nitrogen SCHEMBL4600490 0.96 EPHX1 (0.74) EPHX1HDAC1HDAC8HDAC6MAPT
Nitrogen SCHEMBL1785874 0.95 EPHX1 (0.72) EPHX1HDAC1HDAC8HDAC6MAPT
Nitrogen SCHEMBL8004821 0.90 EPHX1 (0.67) EPHX1HDAC1HDAC8HDAC6MAPT
SCHEMBL669522 0.88 EPHX1 (0.64) EPHX1HDAC1HDAC8HDAC6MAPT
SCHEMBL5947431 0.85 MAPT (0.67) EPHX1HDAC1HDAC8HDAC6MAPT
SCHEMBL11328524 0.85 HDAC1 (0.72) EPHX1HDAC1HDAC8HDAC6MAPT
Nitrogen SCHEMBL4600884 0.84 MAPT (0.77) EPHX1HDAC1HDAC8HDAC6MAPT
Nitrogen SCHEMBL10785749 0.83 EPHX1 (0.58) EPHX1HDAC1HDAC8HDAC6MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107090486-A Product and method for detecting target microorganism 3M创新有限公司 2017-08-25 CN disclosed
CN-103282513-B Articles and methods for detecting target microorganisms 3M创新有限公司 2016-11-16 CN disclosed