Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.77 |
| ▸ | CA6 | P23280 | 5/20 | 0.77 |
| ▸ | CA7 | P43166 | 5/20 | 0.77 |
| ▸ | CA9 | Q16790 | 5/20 | 0.77 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.77 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | RECQL | P46063 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | CA2 | P00918 | 4/20 | 0.71 |
| ▸ | CA4 | P22748 | 4/20 | 0.71 |
| ▸ | CA5A | P35218 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | CA3 | P07451 | 3/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.71 |
| ▸ | CA1 | P00915 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,2-Dichloroethane SCHEMBL28083861 | 0.89 | CA12 (0.71) | CA12CA6CA7CA9CA14 | |
| SCHEMBL5314937 | 0.88 | CA12 (1.00) | CA12CA6CA7CA9CA14 | |
| SCHEMBL15381 | 0.88 | — | — | |
| SCHEMBL8901759 | 0.86 | — | — | |
| SCHEMBL3343772 | 0.85 | — | — | |
| Trientine SCHEMBL13685489 | 0.85 | CA12 (0.85) | CA12CA6CA7CA9CA14 | |
| SCHEMBL25340653 | 0.84 | CA12 (1.00) | CA12CA6CA7CA9CA14 | |
| SCHEMBL15797 | 0.84 | CA12 (1.00) | CA12CA6CA7CA9CA14 | |
| SCHEMBL581603 | 0.84 | CA12 (1.00) | CA12CA6CA7CA9CA14 | |
| SCHEMBL25342018 | 0.84 | CA12 (1.00) | CA12CA6CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108517014-A | The antibody and application thereof of Risperidone haptens | 詹森药业有限公司 | 2018-09-11 | — | — | CN | disclosed |
| CN-108495646-A | For treating and/or the compound of nursing skin, hair, nail and/or mucous membrane | 路博润先进材料公司 | 2018-09-04 | — | — | CN | disclosed |
| CN-108349901-A | PHENYL DERIVATIVES AS CANNABINOID RECEPTOR 2 AGONISTS | 豪夫迈·罗氏有限公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-107949388-A | Pharmaceutical salts, physical aspect and composition of pyrrolopyrimidine kinase inhibitor and preparation method thereof | 艾森生物科学公司 | 2018-04-20 | — | — | CN | disclosed |
| CN-104968360-B | For treatment and/or nursing skin, the compound and their make-up and beauty or pharmaceutical composition of hair and/or mucous membrane | 路博润先进材料公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-107674061-A | Pyridine derivate | 霍夫曼-拉罗奇有限公司 | 2018-02-09 | — | — | CN | disclosed |
| CN-107548400-A | The purification process of Carfilzomib | 费森尤斯卡比肿瘤学有限公司 | 2018-01-05 | — | — | CN | disclosed |
| CN-105008343-B | Alternatively benzothiophene derivative of property ERs degradation agent and combinations thereof | 诺华股份有限公司 | 2017-12-08 | — | — | CN | disclosed |
| CN-104837831-B | Novel pyridine derivatives | 霍夫曼-拉罗奇有限公司 | 2017-10-31 | — | — | CN | disclosed |
| CN-104302290-B | Hepatitis c virus inhibitors | 百时美施贵宝公司 | 2017-10-24 | — | — | CN | disclosed |
| CN-107011330-A | BRUTON'S TYROSINE KINASE INHIBITORS | 比奥根MA公司 | 2017-08-04 | — | — | CN | disclosed |
| CN-102711473-B | Bruton's tyrosine kinase inhibitors | 比奥根MA公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-105980376-A | Heterocyclic modulators of lipid synthesis for use against cancer and viral infections | 3-V生物科学股份有限公司 | 2016-09-28 | — | — | CN | disclosed |