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SCHEMBL28099541

SCHEMBL28099541

NC(=O)c1ccc(NC(=O)c2ccc(-n3ccccc3=O)cc2)c(NC(=O)c2cccc(Br)c2)c1

nearest known ligand 0.84

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 18/20 0.84
▸ PARP1 P09874 1/20 0.46
▸ MEN1 O00255 1/20 0.43
▸ ABL1 P00519 1/20 0.43
▸ MAPT P10636 1/20 0.43
▸ TSHR P16473 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ RIN1 Q13671 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28099683 0.91 F10 (1.00) F10
SCHEMBL28099685 0.88 F10 (0.79) F10
SCHEMBL28099687 0.86 F10 (0.83) F10
SCHEMBL28834490 0.85 F10 (0.80) F10MEN1KMT2A
SCHEMBL28099689 0.85 F10 (0.82) F10MEN1KMT2A
SCHEMBL28099691 0.84 F10 (1.00) F10
SCHEMBL28099693 0.82 F10 (1.00) F10
SCHEMBL28099533 0.82 F10 (0.81) F10MEN1KMT2A
SCHEMBL28099696 0.81 F10 (0.73) F10
SCHEMBL28099569 0.79 F10 (1.00) F10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105985276-A 3,4-dibenzamido benzamide derivative, preparation method and application thereof 南京中瑞药业有限公司 2016-10-05 — — CN claimed
CN-105985276-A 3,4-dibenzamido benzamide derivative, preparation method and application thereof 南京中瑞药业有限公司 2016-10-05 — — CN disclosed