Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28100578 | 0.92 | TACR3 (0.44) | TACR3MEN1KMT2APARP1ALDH1A1 | |
| SCHEMBL1070351 | 0.72 | CA12 (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9384941 | 0.71 | MAPT (0.43) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8574143 | 0.71 | CA12 (0.45) | CA12CA1CA2CA7CA9 | |
| SCHEMBL16832920 | 0.71 | NQO2 (0.54) | KMT2APARP1KDM4EATMMMP13 | |
| SCHEMBL2862825 | 0.71 | KDM4E (0.59) | KDM4ESMN1; SMN2MAPT | |
| SCHEMBL8573902 | 0.70 | CA12 (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8569654 | 0.70 | POLB (0.45) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8574343 | 0.70 | CA12 (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10925688 | 0.70 | SMN1; SMN2 (0.37) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106029647-A | Glucose transport inhibitors | 拜耳制药股份公司 | 2016-10-12 | — | — | CN | disclosed |