Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10847537 | 0.88 | DAO (0.51) | L3MBTL1SMN1; SMN2TDP1MAPTALDH1A1 | |
| SCHEMBL14865087 | 0.85 | DAO (0.54) | L3MBTL1SMN1; SMN2TDP1MAPTALDH1A1 | |
| SCHEMBL4612802 | 0.81 | DAO (0.47) | L3MBTL1SMN1; SMN2TDP1MAPTALDH1A1 | |
| SCHEMBL28497830 | 0.81 | GAA (0.54) | L3MBTL1SMN1; SMN2TDP1MAPTALDH1A1 | |
| SCHEMBL28502919 | 0.81 | NPC1 (0.55) | L3MBTL1SMN1; SMN2TDP1MAPTALDH1A1 | |
| SCHEMBL11295149 | 0.81 | KMT2A (0.51) | SMN1; SMN2MAPTALDH1A1LMNADAO | |
| SCHEMBL7508466 | 0.80 | MAOB (0.60) | L3MBTL1SMN1; SMN2TDP1MAPTALDH1A1 | |
| SCHEMBL11205707 | 0.80 | DAO (0.50) | L3MBTL1SMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL3522886 | 0.80 | DAO (0.47) | L3MBTL1SMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL28543149 | 0.78 | HPGD (0.58) | SMN1; SMN2TDP1MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112521240-B | Synthesis method of asymmetric thioether | 扬州大学 | 2023-06-30 | — | — | CN | disclosed |
| CN-112521240-A | Method for synthesizing asymmetric thioether | 扬州大学 | 2021-03-19 | — | — | CN | disclosed |
| CN-106008298-A | Green method for preparing asymmetric thioether from alcohol and mercaptan | 温州大学 | 2016-10-12 | — | — | CN | disclosed |