SCHEMBL28101232

SCHEMBL28101232

C=C=O.NC(=O)NC(N)=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.45
TSHR P16473 3/20 0.39
LMNA P02545 3/20 0.39
NFKB1 P19838 2/20 0.39
CYP1A2 P05177 2/20 0.39
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
THPO P40225 1/20 0.39
CA2 P00918 1/20 0.39
CYP3A4 P08684 1/20 0.39
CA5A P35218 1/20 0.39
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
CA9 Q16790 1/20 0.39
MAPT P10636 1/20 0.32
CACNA1B Q00975 1/20 0.32
APBA1 Q02410 1/20 0.32
ALDH1A1 P00352 2/20 0.31
OR51E2 Q9H255 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formaldehyde SCHEMBL27917370 0.82
SCHEMBL27939070 0.82 CRBN (0.60) CRBNTSHRLMNANFKB1CYP1A2
SCHEMBL27524722 0.82 CRBN (0.60) CRBNTSHRLMNANFKB1CYP1A2
SCHEMBL15045 0.82
SCHEMBL27560286 0.82 CRBN (0.60) CRBNTSHRLMNANFKB1CYP1A2
SCHEMBL491201 0.80 CRBN (0.45) CRBNTSHRLMNANFKB1CYP1A2
SCHEMBL476197 0.80 CRBN (0.45) CRBNTSHRLMNANFKB1CYP1A2
Hydrazinecarboxamide SCHEMBL29036173 0.80
SCHEMBL5474405 0.80 CRBN (0.45) CRBNTSHRLMNANFKB1CYP1A2
SCHEMBL9806140 0.80 CRBN (0.45) CRBNTSHRLMNANFKB1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105985661-A Wavelength conversion layer on a glass plate to enhance solar harvesting efficiency 日东电工株式会社 2016-10-05 CN disclosed