SCHEMBL2810142

SCHEMBL2810142

NC(N)c1cccc(C(=O)O)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 2/20 0.68
ENPEP Q07075 2/20 0.68
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA9 Q16790 2/20 0.52
CA12 O43570 1/20 0.52
CA6 P23280 1/20 0.52
GRM4 Q14833 1/20 0.50
KMO O15229 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2C9 P11712 1/20 0.48
HPGD P15428 1/20 0.48
HSD17B10 Q99714 1/20 0.48
UNG P13051 1/20 0.47
DAO P14920 1/20 0.46
TSHR P16473 1/20 0.46
NAPRT Q6XQN6 1/20 0.46
F2 P00734 1/20 0.46
FOLH1 Q04609 1/20 0.46
AKR1C3 P42330 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Alcohol SCHEMBL27864998 0.96 ANPEP (0.64) ANPEPENPEPCA1CA2CA9
SCHEMBL27997462 0.88 ANPEP (0.68) ANPEPENPEPCA1CA2CA9
SCHEMBL28006680 0.84 MAPT (0.64) ANPEPENPEPCYP1A2CYP2C9HPGD
SCHEMBL505969 0.84 ANPEP (0.64) ANPEPENPEPCA1CA2CA9
SCHEMBL1512908 0.84 ANPEP (0.64) ANPEPENPEPCA1CA2CA9
SCHEMBL7613565 0.84 ANPEP (0.64) ANPEPENPEPCA1CA2CA9
SCHEMBL7613619 0.84 ANPEP (0.64) ANPEPENPEPCA1CA2CA9
SCHEMBL2957369 0.83 ANPEP (0.61) ANPEPENPEPCA1CA2CA9
Hydrochloric Acid SCHEMBL506171 0.82 ANPEP (0.62) ANPEPENPEPCA1CA2CA9
Hydrochloric Acid SCHEMBL10277608 0.82 ANPEP (0.62) ANPEPENPEPCA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102766138-A Preparation method of azilsartan SHANGHAI COUPLING PHARMACEUTICAL R & D CO LTD 2012-11-07 CN claimed
CN-1177967-C Enzymatic method for textile dyeing ŵ����÷�����޹�˾ 2004-12-01 CN claimed
CN-107922430-A 2 substituted benzimidazole, 4 Carbox amide and preparation method and application 中国科学院上海药物研究所 2018-04-17 CN disclosed
CN-105473557-A Process for producing 3, 3-dimethyl-3, 4-dihydro-1H-quinoxalin-2-one derivative and intermediate for the production process SANTEN PHARMACEUTICAL CO LTD 2016-04-06 CN disclosed
CN-104072486-B As the connection-1H-benzoglyoxaline of hepatitis C virus inhibitors SQUIBB BRISTOL MYERS CO. (US) 2016-04-06 CN disclosed
CN-105392498-A Anti-malignant tumor agent composition PHARMA CO LTD J 2016-03-09 CN disclosed
CN-101962488-B The nano-scale particle of benzimidazolone pigment Xerox Corp. (US) Patent Dept. 020 Xerox Square 100 Clinton Avenue Rochester New (US) 2016-02-03 CN disclosed
CN-102807568-B Thiadiazoles derivative class DPP-IV inhibitor CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) 2015-11-25 CN disclosed
CN-104193740-A BENZIMIDAZOLES AND RELATED ANALOGS AS SIRTUIN MODULATORS SIRTRIS PHARMACEUTICALS INC 2014-12-10 CN disclosed
CN-103153986-B Hepatitis c virus inhibitors BRISTOL MYERS SQUIBB CO 2014-11-05 CN disclosed
CN-104072486-A BI-1H-BENZIMIDAZOLES AS HEPATITIS C VIRUS INHIBITORS BRISTOL MYERS SQUIBB CO 2014-10-01 CN disclosed
CN-1110598-C Enzymatic method for dyeing NOVOZYMES NORTHERN AMERICAL AS (US) 2003-06-04 CN disclosed
CN-1110599-C Enzymatic method for textile dyeing NOVOZYMES NORTH AMERICA AS (US) 2003-06-04 CN disclosed
CN-1361101-A New synthesis route of candixatan ester SHANGHAI INST OF PHARMACOLOGY (CN) 2002-07-31 CN disclosed
CN-1353695-A Heterocyclically substituted benzimidazoles, production and application thereof BASF AG (DE) 2002-06-12 CN disclosed
CN-1332731-A Substituted benzimidazoles and their prep. and use BASF AG (DE) 2002-01-23 CN disclosed
CN-1205754-A Enzymatic method for dyeing NOVO NORDISK BIOCHEM INC (US) 1999-01-20 CN disclosed
CN-1205755-A Enzymatic process for dyeing textiles NOVO NORDISK BIOCHEM INC (US) 1999-01-20 CN disclosed
CN-1195985-A Benzimidazole compounds UNIV NEWCASTLE VENTURES LTD (GB) 1998-10-14 CN disclosed
CN-1057257-A The new intermediate of new imdazole derivatives and method for making thereof, gained, as the application of medicine with contain their pharmaceutical composition ROUSSEL UCLAF (FR) 1991-12-25 CN disclosed