Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 12/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30354920 | 0.86 | CYP19A1 (0.62) | CYP19A1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL30354860 | 0.83 | CYP19A1 (0.62) | CYP19A1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL28834633 | 0.83 | CYP19A1 (0.56) | CYP19A1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL3295922 | 0.82 | CYP19A1 (0.64) | CYP19A1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL28101471 | 0.82 | CYP19A1 (0.55) | CYP19A1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL6927459 | 0.81 | CYP19A1 (0.57) | CYP19A1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL6567935 | 0.81 | CYP19A1 (0.54) | CYP19A1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL28216463 | 0.81 | CYP19A1 (0.57) | CYP19A1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL29151267 | 0.80 | CYP19A1 (0.56) | CYP19A1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL16953601 | 0.79 | MAPT (0.55) | CYP19A1NPC1RAB9AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106349122-A | Novel substituted sulfamide compound, preparation method and application thereof as PTP1B inhibitor | 齐鲁工业大学 | 2017-01-25 | — | — | CN | disclosed |