Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | POLB | P06746 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | CRHBP | P24387 | 3/20 | 0.61 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.61 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27472751 | 0.88 | MEN1 (0.72) | MEN1KMT2APOLBGAACRHBP | |
| SCHEMBL28723007 | 0.88 | MEN1 (0.82) | MEN1KMT2APOLBGAACRHBP | |
| SCHEMBL31384411 | 0.85 | MEN1 (0.60) | MEN1KMT2APOLBGAACRHBP | |
| SCHEMBL8650854 | 0.83 | MEN1 (0.66) | MEN1KMT2APOLBGAACRHBP | |
| SCHEMBL4929277 | 0.81 | MEN1 (0.77) | MEN1KMT2APOLBGAAMAPT | |
| SCHEMBL222685 | 0.79 | MEN1 (0.70) | MEN1KMT2APOLBGAACRHBP | |
| SCHEMBL28007431 | 0.78 | MAPT (0.76) | MEN1KMT2APOLBGAACRHBP | |
| SCHEMBL29123185 | 0.78 | CA1 (0.67) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL9592831 | 0.77 | TSHR (0.63) | MEN1KMT2APOLBGAACRHBP | |
| SCHEMBL14641039 | 0.77 | MEN1 (0.67) | MEN1KMT2APOLBGAACRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104327045-B | A kind of acridine thioether analog derivative and its production and use | 广西中医药大学 | 2016-11-30 | — | — | CN | claimed |