Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL1345780 | 0.98 | STAT3 (0.36) | STAT3STAT1 | |
| Alcohol SCHEMBL28281751 | 0.96 | STAT3 (0.35) | STAT3STAT1 | |
| Alcohol SCHEMBL11138760 | 0.92 | STAT3 (0.33) | STAT3STAT1 | |
| Ethylene Glycol SCHEMBL28169592 | 0.88 | STAT3 (0.37) | STAT3STAT1 | |
| Methyl Alcohol SCHEMBL6497173 | 0.87 | STAT3 (0.39) | STAT3STAT1 | |
| SCHEMBL10725319 | 0.87 | STAT3 (0.41) | STAT3STAT1 | |
| SCHEMBL21729 | 0.87 | STAT3 (0.41) | STAT3STAT1 | |
| SCHEMBL27687319 | 0.87 | STAT3 (0.41) | STAT3STAT1 | |
| Alcohol SCHEMBL10570857 | 0.86 | STAT3 (0.31) | STAT3STAT1 | |
| SCHEMBL8507482 | 0.86 | STAT3 (0.36) | STAT3STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106856243-A | A kind of preparation method and application based on transition metal macrocycle ordering single electrode | 大连理工大学 | 2017-06-16 | — | — | CN | disclosed |
| CN-106076420-A | The preparation method and application of cadmium sulfide immobilized four (4 carboxyl phenyl) iron porphyrin catalysis material | 广西大学 | 2016-11-09 | — | — | CN | disclosed |