Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 3/20 | 0.64 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5540736 | 0.86 | AGXT (0.59) | AGXTMRGPRX4MGLL | |
| SCHEMBL28107030 | 0.84 | FFAR1 (0.50) | AGXTMRGPRX4PTPN5MAOAMAOB | |
| SCHEMBL95134 | 0.81 | IDO1 (0.58) | AGXTTAAR1MAOAMAOB | |
| SCHEMBL15677919 | 0.81 | PRKCI (0.56) | AGXTMGLL | |
| SCHEMBL27860858 | 0.79 | TSHR (0.43) | AGXTMGLLMAOAMAOBAR | |
| SCHEMBL11394076 | 0.78 | MAOB (0.39) | AGXTMAOAMAOB | |
| SCHEMBL28067598 | 0.77 | AGXT (0.46) | AGXTMRGPRX4MGLLMAOAMAOB | |
| SCHEMBL95539 | 0.77 | IDO1 (0.52) | AGXTMAOAMAOB | |
| SCHEMBL20493836 | 0.75 | AGXT (0.65) | AGXTMRGPRX4MGLLPTPN5TAAR1 | |
| SCHEMBL15164027 | 0.75 | PPARA (0.48) | MRGPRX4MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106029633-A | Sulfonamide derivative or pharmaceutically acceptable acid addition salt thereof | 国立大学法人筑波大学 | 2016-10-12 | — | — | CN | disclosed |