Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT4 | P35916 | 13/20 | 0.52 |
| ▸ | PTK2 | Q05397 | 7/20 | 0.49 |
| ▸ | KDR | P35968 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15506655 | 0.83 | FLT4 (0.68) | FLT4KDR | |
| SCHEMBL28107721 | 0.82 | FLT4 (0.54) | FLT4PTK2KDR | |
| SCHEMBL15566846 | 0.81 | FLT4 (0.69) | FLT4PTK2KDR | |
| SCHEMBL28019630 | 0.79 | FLT4 (0.69) | FLT4PTK2 | |
| SCHEMBL15506657 | 0.77 | FLT4 (0.71) | FLT4KDR | |
| SCHEMBL28107726 | 0.76 | PTK2 (0.73) | FLT4PTK2KDR | |
| SCHEMBL27949158 | 0.72 | PTK2 (0.79) | FLT4PTK2 | |
| SCHEMBL27933739 | 0.71 | PTK2 (0.77) | FLT4PTK2 | |
| SCHEMBL15524821 | 0.70 | PTK2 (0.65) | FLT4PTK2 | |
| SCHEMBL15506865 | 0.70 | FLT4 (0.82) | FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104736533-B | Vegfr3 inhibitor | 癌症治疗合作研究中心有限公司 | 2016-12-07 | — | — | CN | claimed |