Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.50 |
| ▸ | F2 | P00734 | 2/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TMPRSS15 | P98073 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770674 | 0.83 | NPC1 (0.51) | PRSS1PRSS2PRSS3SMN1; SMN2NPSR1 | |
| SCHEMBL8770226 | 0.83 | NPC1 (0.51) | PRSS1PRSS2PRSS3SMN1; SMN2NPSR1 | |
| SCHEMBL4262556 | 0.83 | CYP1A2 (0.77) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL7117710 | 0.82 | PRSS1 (0.58) | PRSS1PRSS2PRSS3F2PLAU | |
| SCHEMBL2234094 | 0.82 | KMT2A (0.71) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL11275382 | 0.81 | PARP10 (0.64) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL5790248 | 0.80 | GAA (0.62) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL943227 | 0.80 | GAA (0.62) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL19489229 | 0.80 | SMN1; SMN2 (0.58) | PRSS1PRSS2PRSS3SMN1; SMN2ST14 | |
| SCHEMBL19486253 | 0.80 | SMN1; SMN2 (0.58) | PRSS1PRSS2PRSS3SMN1; SMN2ST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106164072-B | Monocyclic lactam organic compounds for the treatment of bacterial infections | 诺华股份有限公司 | 2019-10-01 | — | — | CN | disclosed |
| CN-106164072-A | Monocyclic lactam organic compounds for the treatment of bacterial infections | 诺华股份有限公司 | 2016-11-23 | — | — | CN | disclosed |