Tert-Butanol

Tert-Butanol

SCHEMBL28110403

C=CC(=O)OC(C)(C)C.CC(C)(C)O

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.37
ALDH1A1 P00352 5/20 0.35
TP53 P04637 3/20 0.35
HIF1A Q16665 3/20 0.35
CYP3A4 P08684 2/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HPGD P15428 1/20 0.35
DGAT1 O75907 1/20 0.34
HSD17B10 Q99714 1/20 0.34
THRB P10828 1/20 0.33
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30658 0.95
SCHEMBL28051179 0.95 TSHR (0.39) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28881367 0.92 TSHR (0.38) TSHRALDH1A1TP53HIF1ACYP3A4
Ammonia Solution, Strong SCHEMBL1020874 0.92 TSHR (0.38) TSHRALDH1A1TP53HIF1ACYP3A4
Water SCHEMBL27303949 0.92 TSHR (0.38) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL29167478 0.92 TSHR (0.38) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL31210190 0.92 TSHR (0.38) TSHRALDH1A1TP53HIF1ACYP3A4
Ammonia Solution, Strong SCHEMBL1707597 0.92 TSHR (0.38) TSHRALDH1A1TP53HIF1ACYP3A4
Phosphine SCHEMBL28845129 0.92 TSHR (0.38) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28190076 0.92 TSHR (0.38) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106040282-A SO 3H-SBA-15 molecular sieve catalyst for catalyzing synthesis of tert-butyl carboxylate from isobutene and carboxylic acid, and preparation method and application thereof 南京工业大学 2016-10-26 CN disclosed