Chlorobenzene

Chlorobenzene

SCHEMBL28110690

Clc1ccccc1.[MgH2].[c]1ccccc1

nearest known ligand 0.61

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.61
CYP1A2 P05177 1/20 0.43
LMNA P02545 3/20 0.37
CYP2A6 P11509 1/20 0.37
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
ORAI1 Q96D31 1/20 0.36
ORAI2 Q96SN7 1/20 0.36
ORAI3 Q9BRQ5 1/20 0.36
TRPV6 Q9H1D0 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.34
MAPT P10636 1/20 0.34
IDO1 P14902 2/20 0.32
TDO2 P48775 2/20 0.32
KMT2A Q03164 2/20 0.32
KDM4E B2RXH2 1/20 0.32
GAA P10253 1/20 0.32
MEN1 O00255 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
HDAC8 Q9BY41 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorobenzene SCHEMBL9591639 0.97 TSHR (0.65) TSHRCYP1A2LMNACYP2A6CES2
Chlorobenzene SCHEMBL8667335 0.82
Chlorobenzene SCHEMBL28029751 0.82
Chlorobenzene SCHEMBL126494 0.82
Chlorobenzene SCHEMBL1669887 0.82
SCHEMBL9732385 0.81 TSHR (0.44) TSHRLMNAMAPTIDO1KMT2A
Chlorobenzene SCHEMBL27345408 0.78
Chlorobenzene SCHEMBL28301912 0.78
Chlorobenzene SCHEMBL7445305 0.78
SCHEMBL24715429 0.78 TSHR (1.00) TSHRCYP1A2LMNACYP2A6CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106132939-B Process for producing tetrazolinone compound 住友化学株式会社 2018-11-13 CN disclosed
CN-108409678-A The manufacturing method of Terazololine-one compound 住友化学株式会社 2018-08-17 CN disclosed
CN-106132939-A Process for producing tetrazolinone compound 住友化学株式会社 2016-11-16 CN disclosed