Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 8/20 | 0.63 |
| ▸ | CARM1 | Q86X55 | 11/20 | 0.60 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28530109 | 0.88 | KLKB1 (0.57) | KLKB1CARM1F2F10PRSS1 | |
| SCHEMBL28111078 | 0.87 | KLKB1 (0.67) | KLKB1CARM1F2F10PRSS1 | |
| SCHEMBL31067518 | 0.86 | KLKB1 (0.72) | KLKB1CARM1 | |
| SCHEMBL31744210 | 0.86 | KLKB1 (0.70) | KLKB1CARM1 | |
| SCHEMBL18604753 | 0.86 | KLKB1 (0.70) | KLKB1CARM1 | |
| SCHEMBL31744170 | 0.86 | KLKB1 (0.72) | KLKB1CARM1 | |
| SCHEMBL18604749 | 0.86 | KLKB1 (0.72) | KLKB1CARM1 | |
| SCHEMBL17064626 | 0.85 | KLKB1 (0.69) | KLKB1CARM1 | |
| SCHEMBL18604751 | 0.85 | KLKB1 (0.68) | KLKB1CARM1 | |
| SCHEMBL17064709 | 0.85 | KLKB1 (0.68) | KLKB1CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307772-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-113307772-A | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2021-08-27 | — | — | CN | disclosed |
| CN-106257976-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2021-02-02 | — | — | CN | disclosed |
| CN-106257976-A | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2016-12-28 | — | — | CN | disclosed |