Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 20/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17064369 | 0.94 | KLKB1 (0.94) | KLKB1 | |
| SCHEMBL18604710 | 0.93 | KLKB1 (0.74) | KLKB1 | |
| SCHEMBL18604682 | 0.92 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL18604748 | 0.91 | KLKB1 (0.89) | KLKB1 | |
| SCHEMBL18604688 | 0.90 | KLKB1 (0.93) | KLKB1 | |
| SCHEMBL18604801 | 0.89 | KLKB1 (0.90) | KLKB1 | |
| SCHEMBL29732859 | 0.88 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL17064586 | 0.88 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL29825726 | 0.88 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL28111107 | 0.88 | KLKB1 (0.81) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106257976-A | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2016-12-28 | — | — | CN | disclosed |