Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 15/20 | 0.83 |
| ▸ | F2 | P00734 | 2/20 | 0.69 |
| ▸ | F10 | P00742 | 2/20 | 0.69 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.69 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.69 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.69 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28111170 | 0.89 | KLKB1 (0.79) | KLKB1F2F10PRSS1PRSS2 | |
| SCHEMBL31067583 | 0.85 | KLKB1 (0.89) | KLKB1F2F10PRSS1PRSS2 | |
| SCHEMBL18604968 | 0.85 | KLKB1 (0.89) | KLKB1F2F10PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL31067585 | 0.85 | KLKB1 (0.87) | KLKB1F2F10PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL18604713 | 0.85 | KLKB1 (0.87) | KLKB1F2F10PRSS1PRSS2 | |
| SCHEMBL31067520 | 0.84 | KLKB1 (0.87) | KLKB1CARM1 | |
| SCHEMBL30415357 | 0.84 | KLKB1 (0.87) | KLKB1CARM1 | |
| SCHEMBL17064482 | 0.84 | KLKB1 (0.87) | KLKB1CARM1 | |
| SCHEMBL18604685 | 0.84 | KLKB1 (0.87) | KLKB1CARM1 | |
| SCHEMBL17064713 | 0.83 | KLKB1 (0.84) | KLKB1CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106257976-A | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2016-12-28 | — | — | CN | disclosed |